recombinant mouse lrpap protein Search Results


94
R&D Systems recombinant mouse lrpap
( a ) Northern blot analysis to detect Toc-siRNA antisense strand in lymph from mouse 2 h after administrated by LNP with Toc-siRNA. AS: Antisense strand of Toc-siRNA. ( b ) FCS analyses (diffusion times) of Cy3-labeled Toc-siRNA in lymph extracted from mice 2 h after colorectal administration and of Nile Red-labeled, FPLC-fractionated lipoproteins prepared from untreated mice. CM, chylomicron; VLDL, very-low-density lipoprotein; LDL, low-density lipoprotein; HDL, high-density lipoprotein. n = 3, mean values ± s.e.m; * P < 0.05. ( c,d ) Confocal images of mouse livers 4 h after colorectal administration of LNP in the fasting state ( c ) or after feeding of milk and intravenous injection of an LPL inhibitor 30 min prior to dosing ( d ). Red: Cy3-labeled Toc-siRNA, Green: FITC-Phalloidin, Blue: TO-PRO-3, Bar = 20 μm. ( e ) Northern blot analysis to detect Toc-siRNA antisense strands in the livers from LNP (with Toc-siRNA) administrated wildtype or <t>LRPAP-injected</t> LDLR -/- mouse. U6 was used as a loading control. AS: Antisense strand of Toc-siRNA.
Recombinant Mouse Lrpap, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+mouse+lrpap+protein/Recombinant+Mouse+LRPAP+Protein%2C+CF/pmc04655470-137-16-19
Average 94 stars, based on 1 article reviews
recombinant mouse lrpap - by Bioz Stars, 2026-11
94/100 stars
  Buy from Supplier

94
R&D Systems recombinant mouse lrpap protein
( a ) Northern blot analysis to detect Toc-siRNA antisense strand in lymph from mouse 2 h after administrated by LNP with Toc-siRNA. AS: Antisense strand of Toc-siRNA. ( b ) FCS analyses (diffusion times) of Cy3-labeled Toc-siRNA in lymph extracted from mice 2 h after colorectal administration and of Nile Red-labeled, FPLC-fractionated lipoproteins prepared from untreated mice. CM, chylomicron; VLDL, very-low-density lipoprotein; LDL, low-density lipoprotein; HDL, high-density lipoprotein. n = 3, mean values ± s.e.m; * P < 0.05. ( c,d ) Confocal images of mouse livers 4 h after colorectal administration of LNP in the fasting state ( c ) or after feeding of milk and intravenous injection of an LPL inhibitor 30 min prior to dosing ( d ). Red: Cy3-labeled Toc-siRNA, Green: FITC-Phalloidin, Blue: TO-PRO-3, Bar = 20 μm. ( e ) Northern blot analysis to detect Toc-siRNA antisense strands in the livers from LNP (with Toc-siRNA) administrated wildtype or <t>LRPAP-injected</t> LDLR -/- mouse. U6 was used as a loading control. AS: Antisense strand of Toc-siRNA.
Recombinant Mouse Lrpap Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+mouse+lrpap+protein/Recombinant+Mouse+LRPAP+Protein%2C+CF/pm38856043-274-11-28
Average 94 stars, based on 1 article reviews
recombinant mouse lrpap protein - by Bioz Stars, 2026-11
94/100 stars
  Buy from Supplier

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The Recombinant Mouse LRPAP Protein from Novus Biologicals is derived from E coli The Recombinant Mouse LRPAP Protein has been validated for the following applications SDS Page
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Mouse LRPAP Recombinant Protein expressed in E. coli with His-tag. Sequence domain: 29-360aa. Application(s): SDS-PAGE.
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N/A
The Recombinant Mouse LRPAP Protein from R D Systems is derived from E coli The Recombinant Mouse LRPAP Protein has been validated for the following applications Binding Activity
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Image Search Results


( a ) Northern blot analysis to detect Toc-siRNA antisense strand in lymph from mouse 2 h after administrated by LNP with Toc-siRNA. AS: Antisense strand of Toc-siRNA. ( b ) FCS analyses (diffusion times) of Cy3-labeled Toc-siRNA in lymph extracted from mice 2 h after colorectal administration and of Nile Red-labeled, FPLC-fractionated lipoproteins prepared from untreated mice. CM, chylomicron; VLDL, very-low-density lipoprotein; LDL, low-density lipoprotein; HDL, high-density lipoprotein. n = 3, mean values ± s.e.m; * P < 0.05. ( c,d ) Confocal images of mouse livers 4 h after colorectal administration of LNP in the fasting state ( c ) or after feeding of milk and intravenous injection of an LPL inhibitor 30 min prior to dosing ( d ). Red: Cy3-labeled Toc-siRNA, Green: FITC-Phalloidin, Blue: TO-PRO-3, Bar = 20 μm. ( e ) Northern blot analysis to detect Toc-siRNA antisense strands in the livers from LNP (with Toc-siRNA) administrated wildtype or LRPAP-injected LDLR -/- mouse. U6 was used as a loading control. AS: Antisense strand of Toc-siRNA.

Journal: Scientific Reports

Article Title: Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route

doi: 10.1038/srep17035

Figure Lengend Snippet: ( a ) Northern blot analysis to detect Toc-siRNA antisense strand in lymph from mouse 2 h after administrated by LNP with Toc-siRNA. AS: Antisense strand of Toc-siRNA. ( b ) FCS analyses (diffusion times) of Cy3-labeled Toc-siRNA in lymph extracted from mice 2 h after colorectal administration and of Nile Red-labeled, FPLC-fractionated lipoproteins prepared from untreated mice. CM, chylomicron; VLDL, very-low-density lipoprotein; LDL, low-density lipoprotein; HDL, high-density lipoprotein. n = 3, mean values ± s.e.m; * P < 0.05. ( c,d ) Confocal images of mouse livers 4 h after colorectal administration of LNP in the fasting state ( c ) or after feeding of milk and intravenous injection of an LPL inhibitor 30 min prior to dosing ( d ). Red: Cy3-labeled Toc-siRNA, Green: FITC-Phalloidin, Blue: TO-PRO-3, Bar = 20 μm. ( e ) Northern blot analysis to detect Toc-siRNA antisense strands in the livers from LNP (with Toc-siRNA) administrated wildtype or LRPAP-injected LDLR -/- mouse. U6 was used as a loading control. AS: Antisense strand of Toc-siRNA.

Article Snippet: In the LDLR –/– mouse study, Toc-siRNA was colorectally administered immediately after injection of 0.8 mg/kg recombinant mouse LRPAP (R&D Systems, MN) via the tail vein.

Techniques: Northern Blot, Diffusion-based Assay, Labeling, Injection, Control